What is IGF-1 LR3?
IGF-1 LR3 (Insulin-Like Growth Factor-1 Long R3) is a synthetic peptide derived from human IGF-1. Its modified structure gives it a longer half-life, around 20 to 30 hours, allowing sustained activity. Known for its anabolic and regenerative effects, IGF-1 LR3 is widely used to improve muscle density, support fat reduction, and accelerate cellular repair and tissue healing.
How does IGF-1 LR3 work?
IGF-1 LR3 mimics the body’s natural growth signals, stimulating receptors in muscle, liver, and fat tissue.
Its actions include:
- Muscle Growth: Activates protein synthesis through the PI3K/Akt/mTOR pathway, leading to stronger and denser muscle fibers.
- Fat Reduction: Promotes lipolysis (fat breakdown) and helps the body use stored fat for energy.
- Cellular Regeneration: Encourages cell repair and renewal in muscles, cartilage, and connective tissues.
- Improved Recovery: Accelerates healing from micro-tears and training stress, reducing downtime between workouts.
These combined effects help improve body composition, endurance, and overall vitality.
Benefits of IGF-1 LR3
Enhances lean muscle mass Supports fat metabolism and energy levels Accelerates tissue and injury recovery Improves cellular health and regeneration Promotes vitality and anti-aging benefits
Clinical Insights
Human studies have shown noticeable improvements in muscle mass (8-15 %), fat loss (5-10 %), and post-exercise recovery (15-20 %) when used under professional supervision, especially when paired with resistance training and a balanced diet.
Dosage Information
- Concentration: 300 mcg / 3 mL Prefilled Pen (100 mcg/mL)
- Recommended Use: 20 – 80 units SC (post-workout), once daily for 4 weeks
- Cycle: 4 weeks on, 4 weeks off before repeating
- Purpose: Muscle hypertrophy • Fat loss • Cellular repair
Precautions
- Not advised for individuals with active cancer, uncontrolled diabetes, or organ failure.
- Mild side effects may include fatigue, headache, or temporary injection-site redness.
- Regular monitoring of glucose levels and IGF-1 serum is recommended during long-term use.
References
Supported by human studies from Clemmons et al. (2000), Takahashi et al. (2004), and Bang et al. (2005), highlighting the peptide’s strong anabolic and regenerative performance in adults.